Executive Summary
The Buck Institute for Research on Aging has been awarded up to $52 million from the U.S. Advanced Research Projects Agency for Health (ARPA-H) to lead Personalized Analytics for Transforming Health (PATH)—a four-year initiative designed to shift healthcare from reactive treatment to proactive, personalized prevention.
Led by the Buck Institute in collaboration with Phenome Health and a national network of partners, PATH aims to develop advanced AI-driven analytics that integrate biological, clinical, behavioral, and environmental data to predict disease risk earlier and more accurately. By identifying subtle, preclinical signals of chronic disease, the program seeks to enable earlier interventions that preserve healthspan and reduce long-term healthcare burden.
The award positions the Buck Institute as a national leader in healthspan-focused data science and reflects ARPA-H’s mandate to fund high-impact, transformative approaches to human health. PATH exemplifies a new model of precision health—one that combines large-scale data, ethical AI, and translational science to proactively support healthier lives.
Official Press Release:
Buck Institute for Research on Aging — Buck Institute and Phenome Health Awarded Up to $52M from ARPA-H for PATH