Buck–IHLAD Precision Health & Longevity Project (UAE)

Buck–IHLAD Precision Health & Longevity Project (UAE)

A National Partnership to Redefine Healthspan Through Genomics, AI & Data Integration

Project Overview

The Price Lab at the Buck Institute for Research on Aging has partnered with the Institute for Healthier Living Abu Dhabi (IHLAD) in the United Arab Emirates to pioneer one of the world’s most ambitious national precision health programs.

The UAE has already achieved a historic milestone—sequencing more than 230,000 citizens’ genomes as part of a whole-nation effort to unlock the genetic foundations of health and longevity.

Building on this unprecedented resource, the Buck–IHLAD collaboration is creating AI-driven multi-omics and exposome models that bridge genomics, clinical biomarkers, lifestyle, and environmental data to extend healthy human lifespan.

Infobox

Lead Partners: Buck Institute, IHLAD

Project Type: National Precision Health Initiative

Participants: 750,000+ UAE citizens

Status: Active

Focus Areas: Genomics | Multi-omics | AI | Exposome | Population Health

Partners:

Scientific aims

To translate population-scale genomic and environmental data into actionable, prevention-focused healthspan insights for the UAE population.

Population-Specific Polygenic Risk Models

Develop Emirati-specific genomic risk prediction models for obesity, cardiovascular disease, diabetes, and cancers—benchmarked against UK Biobank and All of Us.

Genomic–Phenomic GAP Analysis

Quantify the divergence between genetic risk and observed health outcomes to identify modifiable, prevention-focused intervention targets.

Biological Age Modeling

Build the first Emirati biological age and wellness index, integrating genomic, metabolic, and environmental markers to set new national reference ranges.

Exposome & Environmental Health Mapping

Model how air quality, water quality, heat exposure, and urban living conditions shape long-term healthspan. Deliver the UAE’s first Exposome Risk Map.

Project impact

A first-of-its-kind national effort translating population-scale science into equitable, actionable healthspan impact.

For Science

  • New and currently nonexistent ancestry-specific models
  • Federated analysis frameworks
  • Multi-omics + exposome integration at national scale

For Society

  • Early detection and prevention pathways
  • National baseline for biological age
  • Science-driven longevity for all citizens

For Partners

  • Proven model for ethical population-scale AI
  • Blueprint for national precision health rollouts
  • Scalable roadmaps for payors, governments, and health systems

Objectively plagiarize interoperable potentialities via end-to-end web-readiness. Proactively impact timely.

Interested in joining the team?

Join a mission-driven team committed to advancing science, innovation, and human health. Explore opportunities to grow your career while making a real impact.